September 17, 2024 Updated on September 09, 2026
Egg Quality+: A preconception supplement to support egg quality and mitochondrial health
If you are trying to conceive, especially in your mid-thirties or later, you have probably run into the phrase "egg quality" more times than you can count. It comes up in fertility forums, in the notes from your provider, and in the quiet worries that surface at two in the morning. What most people are really asking is a simple, hopeful question: is there anything I can actually do to support my eggs before I try to conceive?
The answer is more encouraging than the headlines suggest. While age does influence fertility, the months leading up to conception are a genuine window of opportunity, not a verdict. This is the thinking behind an egg quality supplement like Egg Quality+, a targeted antioxidant formula WeNatal designed to support egg cell energy and mitochondrial health during that preconception window, working alongside your foundational WeNatal for Her prenatal rather than replacing it.
Egg Quality+ is a preconception supplement that layers targeted antioxidant and mitochondrial support on top of a foundational prenatal. It combines CoQ10, N-acetyl cysteine (NAC), alpha-lipoic acid (ALA), acetyl L-carnitine, and PQQ, ingredients studied for their roles in cellular energy production and in helping the body counter oxidative stress. It is designed for the roughly three to four months before ovulation, and it is formulated to be taken together with WeNatal for Her, not on its own.
Key takeaways
- Egg quality is not fixed. The three to four months before ovulation are an active window in which nutrition and lifestyle may support the egg cells maturing during that time.
- Mitochondria, the cell's energy generators, are unusually abundant in egg cells, and their function is closely tied to how egg cells produce the energy they rely on.
- Egg Quality+ delivers a blend of antioxidants and amino acids selected for their studied roles in cellular energy and oxidative stress, including CoQ10, NAC, ALA, acetyl L-carnitine, and PQQ.
- Recent meta-analyses have looked at antioxidants and CoQ10 in women with age-related fertility challenges, with some encouraging signals.
- Egg Quality+ is designed to work alongside WeNatal for Her, and it is one supportive piece of a larger picture that also includes whole-body health, your partner's health, and personalized guidance from your provider.
What is Egg Quality+?
Egg Quality+ is a preconception supplement built around a single idea: the egg cells preparing to ovulate over the next few months rely heavily on energy, and that energy comes from the mitochondria inside them. The formula pairs antioxidants with amino acids that have been studied for their roles in mitochondrial energy production and in helping the body manage oxidative stress.
WeNatal prenatals were formulated to provide essential, foundational nutrition across the whole journey. WeNatal for Her nourishes women and the developing baby from trying-to-conceive through pregnancy and postpartum, and WeNatal for Him supports healthy sperm, which is an equally important half of the equation. Together, these prenatals lay the groundwork by helping fill nutrient gaps and supporting whole-body reproductive health.
Egg Quality+ is different in scope. Rather than covering broad foundational nutrition, it adds a focused layer of antioxidant support for people who want extra support during preconception, particularly women over 35. It’s intended to be taken alongside WeNatal for Her, so the two work as a system rather than as competing products.
Egg Quality+ at a glance
Take 3 capsules per day with food. Because CoQ10 is fat-soluble, pairing Egg Quality+ with a meal that includes healthy fats, such as avocado, olive oil, nuts, or seeds, may help your body absorb it more effectively.
Why mitochondrial health matters for egg quality
Mitochondria are often called the powerhouse of the cell because they convert the food we eat into usable energy. Egg cells are especially rich in mitochondria, more than almost any other cell in the body, which is why mitochondrial health is so closely connected to egg cell health.
As we get older, mitochondrial function naturally shifts, and egg cells can become less efficient at producing the energy that maturation requires. This is one reason the preconception window matters. The egg cells preparing to ovulate over the next three to four months are actively maturing during that time, which means the choices you make now, from nutrition to lifestyle, may support them along the way.
To go deeper on the biology, our companion piece on why mitochondrial health matters for egg quality walks through how these tiny structures fuel the egg maturation process.
Is egg quality really something you can support?
Scientists once believed egg quality was entirely fixed and simply declined with age. We now understand the picture is more nuanced. Age matters, but so does the environment those egg cells mature in during the months before ovulation. That short window is exactly where a targeted preconception routine is designed to help, which is a genuinely hopeful message for anyone who has felt that age was the whole story. WeNatal co-founder Ronit shares her own experience in how she approached egg quality after 40.
How does Egg Quality+ support egg quality?
Egg Quality+ was formulated around a few complementary mechanisms, each tied to how egg cells produce and protect their energy supply. Here is what each part of the blend is there to do.
- Supports mitochondrial function. Mitochondria turn nutrients into the cellular energy egg cells depend on. Ingredients like CoQ10 and PQQ have been studied for their roles in mitochondrial energy production and in supporting the body's own production of new mitochondria.
- Supports the body's antioxidant defenses. Antioxidants such as NAC and alpha-lipoic acid have been studied for their ability to help the body counter oxidative stress, which is a normal part of cellular life that the body works to keep in balance.
- Supports the body's natural hormone production. Acetyl L-carnitine has been studied for its role in cellular energy transport and in supporting the body's normal hormone production.
- Supports egg quality. Research on this blend of antioxidants and amino acids has looked at how they may support the health of developing egg cells as part of a broader preconception approach.
The through-line is energy. Each ingredient was chosen to support the mitochondrial energy that egg cells rely on as they mature, and to help the body maintain its natural balance against oxidative stress along the way.
Key ingredients in Egg Quality+
CoQ10 (ubiquinone)
CoQ10 is a potent antioxidant and a core component of the mitochondrial energy pathway. It supports cellular energy production and helps the body counter oxidative stress, and it has been studied specifically for its role in mitochondrial function within egg cells. In a widely cited laboratory study, CoQ10 was shown to support oocyte mitochondrial function during reproductive aging, a finding that helped shape interest in CoQ10 for preconception support.
N-acetyl cysteine (NAC)
NAC supports the body's production of glutathione, one of its most important antioxidant molecules. By supporting the body's antioxidant defenses, NAC has been studied in the context of healthy ovarian function, including research in women of advanced reproductive age.
Alpha-lipoic acid (ALA)
ALA supports the conversion of nutrients into energy within mitochondria and acts as an antioxidant in its own right. A systematic review of ALA in reproductive health has examined its role in supporting metabolic health and in helping the body counter oxidative stress.
Acetyl L-carnitine
Acetyl L-carnitine helps transport fatty acids into the mitochondria, where they are used for energy, and it has been studied for its role in the body's normal hormone production. A review of L-carnitine in female reproductive health summarizes the research to date.
PQQ (pyrroloquinoline quinone)
PQQ has been studied for its role in supporting the production of new mitochondria, and it is thought to work alongside CoQ10 to support cellular energy generation. It helps activate the cellular machinery involved in mitochondrial renewal and repair.
Who is Egg Quality+ for?
Egg Quality+ was created for people who want to add a focused layer of preconception support on top of their foundational prenatal. It tends to resonate most with:
- Women over 35 who want extra antioxidant support during the preconception window.
- Anyone preparing for conception who wants to support egg cell energy and mitochondrial health in the months before trying.
- People preparing for assisted reproduction or egg freezing who want to support their whole-body health going in, in coordination with their care team.
If you are not sure where to start, our two-minute quiz can help point you toward the right WeNatal products for your stage.
How Egg Quality+ works with WeNatal for Her
Egg Quality+ was designed to work in harmony with WeNatal for Her, not to stand in for it.
- WeNatal for Her is the comprehensive foundation, delivering the essential vitamins and minerals that support health before, during, and after pregnancy.
- Egg Quality+ adds a targeted layer of antioxidant and mitochondrial support focused on the preconception window.
The two are meant to be taken together, which is why many people choose the WeNatal for Her and Egg Quality+ duo and simply take three capsules of each per day with food.
One thoughtful detail: CoQ10 and NAC are included in Egg Quality+ for preconception support, but they were intentionally left out of WeNatal for Her. There is not yet enough research on their use during pregnancy, so WeNatal chose to keep them in the preconception-focused formula rather than the prenatal you continue through pregnancy.
What should partners know?
Fertility has never been a one-person project. Men contribute roughly half of the equation, and sperm health is shaped by many of the same principles that guide egg health: cellular energy, antioxidant balance, and consistent nutrition in the months before conception.
While Egg Quality+ is formulated for egg cells specifically, the partner-inclusive version of this idea is WeNatal for Him, a men's prenatal built to support healthy sperm quality, count, and motility. Many couples choose to prepare together with WeNatal Together, taking both prenatals side by side. If you are curious whether a men's prenatal is worth it, our guide on whether men can take prenatal vitamins is a good starting point.
Preparing as a team can also take some of the quiet pressure off one person to carry the whole journey, which matters just as much as the nutrition itself.
How and when should you take Egg Quality+?
- Dose: Take 3 capsules per day with food.
- Timing: Begin ideally three to four months before you plan to conceive, since that reflects the window in which the relevant egg cells are maturing.
- Absorption: Take it with meals that includes healthy fats to support absorption of fat-soluble CoQ10.
- Pairing: Take it alongside WeNatal for Her for foundational nutrition plus targeted preconception support.
- Egg Quality+ is designed for preconception. Once you are pregnant, transition your focus to WeNatal for Her and talk with your provider about your prenatal routine.
When should you talk to your provider?
Supplements are one supportive piece of a much larger picture, and some situations call for personalized medical guidance first. Talk with your healthcare provider before starting Egg Quality+ if you:
- Are currently pregnant or breastfeeding, since this formula is designed for preconception.
- Are undergoing fertility treatment or working with a reproductive endocrinologist, so your full supplement routine can be coordinated with your care.
- Take prescription medication, including thyroid medication, or have a diagnosed health condition.
- Have questions about whether these ingredients and doses are right for your individual situation.
A good provider relationship is one of the most valuable tools you have. Supplements support your body's foundation, and personalized care helps you make sense of your own unique picture.
Frequently asked questions on egg quality
What is the best supplement to support egg quality?
There is no single "best" supplement, because egg health is influenced by many factors. Antioxidant nutrients like CoQ10, NAC, and alpha-lipoic acid are among the most studied for their roles in cellular energy and oxidative stress, and Egg Quality+ combines these in one formula designed to be taken alongside a foundational prenatal. The most supportive approach pairs a supplement with whole-body health and guidance from your provider.
When should I start taking an egg quality supplement?
A common approach is to begin about three to four months before trying to conceive, since the egg cells preparing to ovulate mature over roughly that window. Starting earlier gives those cells more time in a well-supported environment.
Can I take Egg Quality+ with WeNatal for Her?
Yes. Egg Quality+ is specifically designed to be taken alongside WeNatal for Her. WeNatal for Her provides foundational nutrition, and Egg Quality+ adds targeted antioxidant and mitochondrial support for preconception.
Does CoQ10 improve egg quality?
CoQ10 has a well-studied role in mitochondrial energy production, and recent meta-analyses have looked at CoQ10 in women with age-related fertility challenges with some encouraging signals. That said, researchers describe the overall evidence as still developing, so CoQ10 is best understood as a nutrient that may support egg cell energy rather than a guaranteed outcome. Your provider can help you interpret the research for your situation.
Can I take Egg Quality+ while pregnant?
Egg Quality+ is formulated for the preconception window and includes ingredients, such as CoQ10 and NAC, that have not been sufficiently studied during pregnancy. Once pregnant, focus on WeNatal for Her and talk with your provider about your routine.
Is Egg Quality+ only for women over 35?
No. While it is especially popular with women over 35 who want extra preconception support, it is designed for anyone who wants to support egg cell energy and mitochondrial health in the months before trying to conceive.
A note from WeNatal on supporting egg quality
When we started WeNatal, it was because we had lived the heartbreak and the confusion of the fertility journey ourselves. We know how it feels to want to do everything right, and to wonder whether anything you do actually matters.
Here is what we have come to believe. Egg quality is not a fixed sentence, and the preconception window is a real opportunity rather than a source of pressure. Egg Quality+ is our way of translating that hope into something practical: a targeted, research-informed formula that supports egg cell energy and mitochondrial health, designed to work alongside the foundational nutrition of WeNatal for Her.
No supplement determines your worth or guarantees an outcome. What we can offer is thoughtful support for your body's foundation, for both partners, during a season that deserves care rather than fear.
Explore Egg Quality+, pair it with WeNatal for Her through the duo bundle, or take our quick quiz to find the right starting point for your stage.
References
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Chowanadisai W, Bauerly KA, Tchaparian E, Wong A, Cortopassi GA, Rucker RB. Pyrroloquinoline quinone stimulates mitochondrial biogenesis through cAMP response element-binding protein phosphorylation and increased PGC-1alpha expression. J Biol Chem. 2010;285(1):142-152. doi:10.1074/jbc.M109.030130. https://doi.org/10.1074/jbc.M109.030130
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Shang Y, Song N, He R, Wu M. Antioxidants and fertility in women with ovarian aging: a systematic review and meta-analysis. Adv Nutr. 2024;15(8):100273. doi:10.1016/j.advnut.2024.100273. https://doi.org/10.1016/j.advnut.2024.100273
Showell MG, Mackenzie-Proctor R, Jordan V, Hodgson R, Farquhar C. Antioxidants for female subfertility. Cochrane Database Syst Rev. 2020;8(8):CD007807. doi:10.1002/14651858.CD007807.pub4. https://doi.org/10.1002/14651858.CD007807.pub4
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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always talk with your healthcare provider before starting a new supplement, especially if you are trying to conceive, pregnant, breastfeeding, or taking medication.