The most important nutrients for TTC, pregnancy, postpartum recovery, and breastfeeding

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The most important nutrients for TTC, pregnancy, postpartum recovery, and breastfeeding

Nutrition needs don't stay static across the fertility journey, and neither does your body. From the months leading up to conception through pregnancy, postpartum recovery, and breastfeeding, the essential nutrients for fertility, pregnancy, and postpartum shift in meaningful ways to support hormone health, cellular energy, tissue repair, and your baby's rapid growth and development.

While a food-first approach is always foundational, this season of life often asks for more than diet alone can reliably provide. Increased nutrient needs, nausea, food aversions, sleep disruption, and stress can all make it difficult to consistently meet optimal levels of key vitamins and minerals. A comprehensive prenatal vitamin and male fertility supplement can help bridge these gaps while supporting egg and sperm quality before conception, fetal development during pregnancy, and maternal recovery and resilience postpartum and beyond.


The essential nutrients for fertility, pregnancy, and postpartum shift by stage, but a core set carries through the whole journey: folate, choline, omega-3s (DHA and EPA), iron, iodine, vitamin D, and protein. Needs rise sharply in pregnancy and stay elevated through postpartum and breastfeeding, which is why a food-first diet paired with a well-formulated prenatal helps close the most common gaps. 


Key takeaways

  • Nutrient needs change by phase. Preconception, each trimester, postpartum, and lactation each emphasize different nutrients, though folate, choline, omega-3s, iron, and protein matter across all of them.
  • Food first, supplement to fill the gaps. A colorful, whole-food diet is foundational, and a comprehensive prenatal helps cover the nutrients that are hardest to reach through food alone.
  • Both partners are part of the picture. Sperm and eggs both develop over months before conception, so preconception nutrition matters for her and for him.
  • Postpartum is not the finish line. For many nutrients, needs during breastfeeding are even higher than they were in pregnancy, and continuing a prenatal can support recovery and replenishment.
  • Labs make it personal. Markers like ferritin, vitamin D, B12, and omega-3 status can help you and your provider tailor support to your body.


What nutrients matter most when trying to conceive (TTC)?

Preparing for pregnancy is one of the most transformative seasons in a person's life, physically, emotionally, and nutritionally. Long before a positive test appears, your body is already laying the foundation for conception, healthy embryo development, and a thriving pregnancy. We refer to this preconception phase as Trimester Zero®, and it's a meaningful opportunity to support fertility health for both partners.

By intentionally supporting your nutritional status before conceiving, you build stronger reserves of key vitamins, minerals, and antioxidants that support both partners' reproductive health and lay the groundwork for a healthy pregnancy from day one.

WeNatal Essentials Welcome Kit

WeNatal Essentials Welcome Kit

The everyday routine for couples, at any stage.

Which nutrients support fertility?

Fertility is supported by more than one "magic" nutrient. It is the cumulative effect of many micronutrients working together to support hormone signaling, cellular energy, DNA integrity, and early embryo development. During the preconception window, certain nutrients become especially important for egg quality, ovulation, implantation, and sperm health.


Key nutrients for fertility for her

  • Folate (methylated folate): Folate supports DNA synthesis, methylation, and early fetal neural development. Using a methylated form such as L-5-MTHF may support absorption and use, including for people with common MTHFR gene variants, and it's one reason we talk about methylfolate for both partners.

  • Choline: Choline plays a key role in cell membrane structure, methylation, neurotransmitter synthesis, and early placental development. National survey data suggest that only about 8 percent of adults, and a similar share of pregnant women, meet recommended choline intake from food, which is why it deserves attention well before pregnancy.

  • Omega-3 fatty acids (DHA): DHA plays a role in a healthy inflammatory response and in normal reproductive hormone signaling, and higher omega-3 intake has been associated with healthier reproductive hormone patterns in some studies. You can read more in our guide to DHA and omega-3s in pregnancy.

  • CoQ10: Coenzyme Q10 is central to mitochondrial energy (ATP) production inside cells, including egg cells, and it also acts as an antioxidant. In a randomized controlled trial of women under 35 with lower ovarian reserve, 60 days of CoQ10 before an IVF cycle was associated with better ovarian response and embryo quality, while differences in pregnancy and live birth rates did not reach statistical significance. It's encouraging early research, and more studies in broader groups of women are still needed.

  • Vitamin D (D3): Vitamin D plays a role in reproductive hormone signaling, immune function, and the uterine lining. Lower vitamin D status has been associated with less favorable fertility outcomes in some studies, which is one reason it's worth checking your levels. Learn more about vitamin D across fertility, pregnancy, and postpartum.

  • Iron and vitamin B12: Iron and vitamin B12 support red blood cell production, oxygen transport, methylation, and overall cellular energy, all of which support the energy demands of a healthy cycle and early pregnancy.

  • Magnesium: Magnesium takes part in hundreds of enzyme reactions, including those involved in the stress response, healthy blood sugar already within the normal range, and sleep quality, which makes it a quiet but foundational part of cycle and hormone health.

  • Zinc and selenium: Both zinc and selenium support healthy follicular development, thyroid hormone conversion, antioxidant protection, and DNA integrity. Low levels of either have been associated with less favorable reproductive outcomes in research.


Key nutrients for fertility for him

Men's fertility deserves equal attention, and nutrition plays a real role in supporting healthy sperm production, motility, morphology, and DNA integrity. Sperm health reflects overall cellular and metabolic health, and what he eats shapes sperm quality months before conception.

  • Antioxidants (vitamin C, vitamin E, glutathione precursors, carotenoids): Antioxidants help protect sperm DNA from oxidative stress, which is a major contributor to reduced sperm motility and DNA fragmentation.

  • Zinc and selenium: Zinc supports normal testosterone production, and both minerals support sperm motility and overall sperm integrity. In a meta-analysis of randomized trials, selenium and zinc supplementation were each associated with improvements in sperm concentration and motility.

  • CoQ10: CoQ10 supports mitochondrial energy production in sperm. In a 2025 network meta-analysis of randomized trials in men with unexplained fertility challenges, CoQ10 was associated with the largest improvement in sperm concentration among the antioxidants studied.

  • L-carnitine: L-carnitine helps transport fatty acids into the mitochondria, supporting sperm energy production. In that same analysis, L-carnitine was associated with the greatest improvement in progressive sperm motility.

  • Omega-3 fatty acids: Omega-3s help maintain sperm membrane fluidity and support a healthy inflammatory response, both of which matter for normal sperm function.


What is the best way to meet these needs?

Supporting fertility works best when nutrition, supplementation, and personalization work together.

A food-first approach remains foundational, emphasizing high-quality proteins, healthy fats, colorful produce, and foods rich in choline, antioxidants, and omega-3s. Fatty fish, pasture-raised eggs, leafy greens, legumes, and mineral-rich whole foods help support hormone health, balance oxidative stress, and nourish developing egg and sperm cells.

Even with a strong diet, optimal intake of key nutrients can be difficult to achieve consistently. A well-formulated prenatal for women, paired with a men's fertility supplement, can help fill micronutrient gaps and support egg and sperm development throughout their multi-month maturation cycles. Look for methylated folate, DHA and EPA, bioavailable minerals, and targeted antioxidants like CoQ10 that support mitochondrial function and reproductive health.

When possible, lab testing can further personalize preconception care. Markers such as vitamin D, ferritin, vitamin B12, thyroid function, and omega-3 status can help identify gaps and guide targeted nutrition. Our guide to pregnancy blood work by trimester is a helpful starting point for the conversation with your provider.

Trying To Conceive Foundation

WeNatal For Him and For Her jars, teal and mauve prenatal supplement containers shown together on a transparent background, offering daily nutrient and fertility support for couples.

Complete nutrition for egg and sperm quality.

Which nutrients are most important in the first trimester?

The first trimester is one of the most nutritionally demanding phases of pregnancy. In just a few short weeks, your baby's organs begin forming, the neural tube closes, and the placenta starts to develop, often before you even know you're pregnant. At the same time, nausea, vomiting, and food aversions can make eating well feel nearly impossible. If you're in the thick of it, our first trimester survival kit has practical ideas for getting through.

Even with those hurdles, a few nutrients matter most during this early stage:

  • Folate and choline: Both support DNA methylation and early brain and organ development, laying the biochemical foundation for healthy growth. Adequate folate before and during early pregnancy may reduce the risk of neural tube defects, which is why providers recommend starting a folate-containing prenatal before conception. You'll find both in leafy greens, lentils, asparagus, avocado, citrus, egg yolks, liver, salmon, and pastured poultry, and we explain how they work together with DHA in choline, folate, and DHA for fetal brain development.

  • Iron: Iron needs begin rising early as blood volume expands, supporting oxygen delivery to both mother and baby. Sources include red meat, lentils, spinach, pumpkin seeds, and iron-fortified foods. Because absorption matters as much as intake, it helps to understand how iron and vitamin C work together.

  • Vitamin B6: Vitamin B6 supports normal protein metabolism, and it is often part of the first steps providers recommend when nausea is making meals hard, so it's worth asking your provider about. Food sources include bananas, potatoes, chickpeas, poultry, sunflower seeds, and salmon.

  • Iodine: Iodine supports maternal thyroid function and early fetal brain development. Food sources include seaweed, eggs, dairy, seafood, and iodized salt.

  • Omega-3 fatty acids (DHA): DHA is essential for early brain and retinal development. Fatty fish such as salmon, sardines, anchovies, trout, and herring are the best food sources.

  • Vitamins D3 and K2: These vitamins work together to support healthy immune function and early bone development. You'll find them in egg yolks, fatty fish, fermented foods, grass-fed butter, cod liver oil, and select full-fat dairy products.

Every Trimester Foundation

Every Trimester Foundation

The perfect pairing for pregnancy and postpartum health.

Which nutrients matter in the second trimester?

By the second trimester, energy and appetite often improve, creating an ideal opportunity to rebuild nutrient stores as fetal growth accelerates. Blood volume continues to expand, protein needs increase, and your baby's skeleton begins to mineralize, placing greater demand on structural and mineral nutrients. For a meal-by-meal view of this stage, our pregnancy nutrition plan by trimester pairs well with the list below.

Here are the key nutrients to prioritize during this stage:

  • Protein: Protein becomes foundational in the second trimester, supplying the amino acids needed for maternal blood volume, fetal tissue growth, enzyme production, and steady energy. High-quality sources include grass-fed beef, poultry, eggs, wild-caught fish, Greek yogurt, cottage cheese, lentils, beans, organic tofu and tempeh, and collagen-rich bone broth. Here's more on how much protein you need in pregnancy and breastfeeding.

  • Calcium, magnesium, and vitamin D: These nutrients work together to support fetal bone development, maternal skeletal integrity, muscle function, and nervous system balance. Calcium-rich foods include dairy, sardines and salmon with bones, tahini, chia seeds, almonds, and broccoli. Magnesium is supplied by pumpkin seeds, leafy greens, avocado, dark chocolate, beans, and whole grains. Vitamin D is best supported through sunlight exposure, fatty fish, and egg yolks.

  • Choline: Choline continues to support brain and placental development, methylation, and cell membrane integrity. Sources include egg yolks, chicken, salmon, shrimp, and legumes.

  • Iron: Iron requirements increase further as red blood cell production rises and fetal demand grows, which is why iron is one of the most common nutrient gaps in pregnancy. Iron-rich foods include red meat, poultry, lentils, beans, spinach, and pumpkin seeds, and pairing them with vitamin C rich foods such as citrus, berries, kiwi, bell peppers, tomatoes, and broccoli supports absorption. If your labs show you need more than your prenatal provides, ask your provider whether a gentle option like WeNatal Iron+, which pairs iron bisglycinate with vitamin C, is a good fit.

  • Omega-3 fatty acids (DHA and EPA): Omega-3s remain essential for ongoing brain, eye, and nervous system development and support a healthy inflammatory response.

  • Fiber and electrolytes: Both play a growing role in supporting digestion, hydration, circulation, and healthy blood volume expansion, common areas of concern in the second trimester. Fiber-rich foods include vegetables, berries, oats, beans, lentils, chia seeds, and flaxseeds. Electrolytes such as sodium, potassium, and chloride come from mineral-rich broths, coconut water, avocados, bananas, root vegetables, and lightly salting whole foods with iodized salt, which also contributes iodine.


Which nutrients are essential in the third trimester?

The third trimester brings another major shift in priorities. Your baby's brain development peaks, fat stores are laid down, and your body begins preparing for labor, delivery, and the postpartum period. Thoughtful, well-balanced nutrition during this stage can help support your energy in the final weeks and lay the groundwork for recovery after birth.

Here are the key nutrients to prioritize in the third trimester:

  • Choline: Choline becomes especially important as fetal brain development accelerates and memory centers rapidly mature. Adequate intake at this stage supports neuronal structure, placental function, and long-term cognitive development.

  • Omega-3 fatty acids (DHA and EPA): DHA and EPA continue to support advanced neural maturation, visual development, and emerging immune function.

  • Iron: Iron remains a high priority to help you enter delivery and the postpartum period with healthy iron stores.

  • Hydration and electrolytes: Each becomes even more important as the body prepares for birth, supporting circulation, nerve signaling, and energy levels.

  • Collagen: Collagen provides amino acids such as glycine and proline that the body uses to build connective tissue, and vitamin C supports the body's own collagen production as skin and tissues stretch in late pregnancy. Collagen-rich foods include bone broth, slow-cooked meats, and collagen peptides, while vitamin C is found in citrus, berries, kiwi, pineapple, bell peppers, and cruciferous vegetables.

  • Protein: Adequate protein remains essential to support rapid fetal growth, preserve maternal muscle mass, support enzyme production, and build nutrient reserves for postpartum recovery. At this stage, sufficient protein also supports steady energy, healthy blood sugar already within the normal range, and satiety. If getting enough protein feels hard right now, WeNatal Prenatal Protein+ for Her combines 20 grams of protein and collagen peptides with prenatal nutrients in one scoop (it's iron-free, so keep a separate iron source if you need one).


What nutrients support postpartum recovery?

The postpartum period, often called the "fourth trimester," places high nutritional demands on the body. After birth, your system is repairing tissues, restoring blood volume, recalibrating hormones, and adjusting to disrupted sleep. Nutrient needs remain elevated, and gaps are common when intake can't keep up, which is why nutrient repletion after pregnancy deserves real attention.

Here are the key nutrients to prioritize for postpartum recovery:

  • Iron: Iron helps replenish losses from delivery and supports oxygen transport, energy levels, and cognitive function. If your ferritin is low, ask your provider whether an added iron supplement such as WeNatal Iron+ makes sense for you.
  • Protein and collagen: Both are essential building blocks for tissue repair, wound healing, and rebuilding connective tissue.
  • Omega-3 fatty acids: Omega-3s support a healthy inflammatory response, nervous system function, and emotional well-being after birth.
  • Choline: Choline supports memory, cognition, nervous system function, and normal liver function during this season of hormonal recalibration.
  • Micronutrients like vitamin D3, K2, B vitamins, magnesium, and iodine: These support immune function, energy production, sleep, nervous system regulation, and thyroid health.

Monitoring nutrient status, particularly ferritin, B12, vitamin D, and omega-3s, helps guide replenishment. Many providers suggest continuing a comprehensive prenatal vitamin for 6 to 12 months after birth, and longer while breastfeeding, alongside nutrient-dense, protein-rich meals that help rebuild strength and support steady energy. If you're wondering how long to keep going, here's our guide on when to stop taking prenatal vitamins.


Which nutrients matter most while breastfeeding?

For many nutrients, needs during breastfeeding are even higher than they were during pregnancy. Your body is continuing to recover from birth while producing nutrient-rich milk to support your baby's growth and development. During this stage, nutrient density, adequate calories and carbohydrates, and hydration become especially important for both infant nourishment and maternal well-being. For a food-focused look at this stage, see nutrition for breastfeeding support.

Here are the key nutrients to prioritize while breastfeeding:

  • Choline: Choline plays a direct role in breast milk composition, supporting infant brain and nervous system development while also supporting maternal liver and cognitive health.
  • Omega-3 fatty acids: DHA and EPA remain vital for infant visual and cognitive development and immune function.
  • Iodine: Iodine supports infant thyroid function and neurological development.
  • Calcium, magnesium, and vitamin D3: These nutrients help support maternal bone health during lactation, a time when calcium is transferred into breast milk.
  • Vitamin B12: B12 supports maternal energy and infant neurodevelopment, and it is particularly important for vegetarian or vegan mothers. Sources include meat, poultry, fish, eggs, and dairy.
  • Protein and healthy fats: Adequate protein and healthy fats help fuel milk production and support steady energy and blood sugar.
  • Hydration and electrolytes: Both help support overall hydration and comfort while your body produces milk around the clock.

You may hear about lactation foods like oats and brewer's yeast. They can be nourishing additions to your plate, though research on their effect on milk supply is limited. Fenugreek is also widely recommended, but the evidence is mixed and it can cause digestive upset for some parents and babies, which is why we left it out of Milk + Mood. Milk + Mood is our fenugreek-free postpartum formula, designed to work alongside WeNatal for Her to support milk supply and mood. The biggest drivers of supply are still frequent, effective milk removal and good lactation support, which our lactation consultant partners cover in what affects milk supply.

Hydrating and nutrient-dense snacks like collagen smoothies, yogurt, nuts, seeds, and eggs provide steady energy through long days and nights of feeding.

Postpartum Foundation

Postpartum Foundation

Foundational nutrition meets targeted postpartum support.


A note for partners: fertility takes two

It is easy for nutrition conversations to center almost entirely on the person carrying the pregnancy. But sperm develop over a multi-month cycle, and the same food-first, antioxidant-rich pattern that supports egg health tends to support sperm health too. That means preconception is a shared window, and it is one of the most encouraging parts of this whole conversation, because sperm are highly responsive to lifestyle. Cooking one fertility-supportive dinner can nourish both partners at once, no separate meal plan required.

If your partner wants a simple place to start, the For Him bundles pair WeNatal for Him with Omega DHA+, with the option to add Rest + Digest Magnesium.

If you are looking for a real, human take on what this looks like in practice, one dad shared his honest experience of sperm health, pregnancy loss, and showing up as half the equation.



Frequently asked questions about nutrients for fertility, pregnancy, and postpartum

What are the most important nutrients when trying to conceive? 

Folate, choline, omega-3s (DHA), vitamin D, iron, B12, magnesium, zinc, and selenium are among the most studied for preconception. For men, zinc, selenium, CoQ10, omega-3s, and antioxidants are frequently studied for sperm health. A food-first diet plus a comprehensive prenatal helps cover the gaps, and lab testing can personalize the picture.


Do nutrient needs really change in each trimester? 

Yes. The first trimester emphasizes folate, choline, iodine, and early DHA. The second trimester raises the priority on protein, iron, and bone-supporting minerals. The third trimester leans on choline, DHA and EPA, iron, protein, and collagen as the body prepares for birth.


Can I get all these nutrients from food alone? 

A whole-food diet is foundational and should come first. That said, nutrients like folate, choline, iodine, DHA, and iron are difficult to reach at optimal levels through food alone during pregnancy and lactation, which is why most providers recommend a prenatal. Talk with your provider about your individual needs.


Should my partner take supplements too? 

Men may benefit from preconception nutrition support, since sperm develop over roughly two to three months. In a meta-analysis of randomized trials, nutrients like zinc, selenium, CoQ10, and omega-3s were associated with improvements in semen parameters. A balanced plate and a men's fertility supplement like WeNatal for Him are a reasonable starting point.


How long should I keep taking a prenatal after birth? 

Many providers suggest continuing a comprehensive prenatal for 6 to 12 months postpartum, and longer if breastfeeding, to support recovery and replenishment. Nutrient demands stay elevated well past delivery, especially during lactation.


Which nutrients matter most for breastfeeding? 

Choline, DHA and EPA, iodine, B12, calcium, magnesium, vitamin D, protein, healthy fats, and steady hydration are the standouts. The levels of several of these in breast milk, including choline, iodine, B12, and DHA, reflect your own intake, so nourishing yourself supports both your recovery and your baby's development.



A note from WeNatal on nourishing the full fertility journey

At WeNatal, we believe fertility and family-building are supported over time, not in isolated moments. From Trimester Zero® through pregnancy, postpartum recovery, and breastfeeding, your nutrient needs evolve, but the goal remains the same: to support both parent and baby with thoughtful, evidence-based nutrition.

Our formulas were designed with these shifting needs in mind. WeNatal for Her and WeNatal for Him provide comprehensive prenatal and fertility support with bioavailable forms of folate, iron, choline, and key micronutrients. Omega DHA+ supports brain, eye, and nervous system development throughout pregnancy and breastfeeding. Egg Quality+ offers targeted mitochondrial and antioxidant support during preconception, Milk + Mood layers fenugreek-free milk supply and mood support onto your postpartum routine, and Rest + Digest Magnesium supports stress resilience, sleep quality, digestion, and nervous system regulation during hormonally demanding seasons.

If you're looking for a more complete roadmap, our free WeNatal Guides bring everything together with nutrition, supplementation support, lifestyle practices, and education for every phase of the fertility journey.

Building a healthy foundation for conception, pregnancy, and beyond isn't about doing more. It's about being supported, consistently, every step of the way.






References

Agarwal A, Parekh N, Panner Selvam MK, et al. Male Oxidative Stress Infertility (MOSI): proposed terminology and clinical practice guidelines for management of idiopathic male infertility. World J Mens Health. 2019;37(3):296-312. doi:10.5534/wjmh.190055. 

American College of Obstetricians and Gynecologists. ACOG Practice Bulletin No. 189: Nausea and vomiting of pregnancy. Obstet Gynecol. 2018;131(1):e15-e30. doi:10.1097/AOG.0000000000002456. 

Amza M, Haj Hamoud B, Sima RM, et al. Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA): should they be mandatory supplements in pregnancy? Biomedicines. 2024;12(7):1471. doi:10.3390/biomedicines12071471. 

Dror DK, Allen LH. Overview of nutrients in human milk. Adv Nutr. 2018;9(suppl_1):278S-294S. doi:10.1093/advances/nmy022. 

Liu J, Mantantzis K, Kaufmann L, et al. Clinical benefits and safety of multiple micronutrient supplementation during preconception, pregnancy, and lactation: a review. Nutr Rev. 2025;83(12):2352-2371. doi:10.1093/nutrit/nuaf079. 

Niu C, Lu X, Xie Y, et al. Effects of carnitine and coenzyme Q10 on sperm quality and pregnancy rates in men with unexplained infertility: a systematic review and network meta-analysis. Reprod Sci. 2025;32(9):2864-2876. doi:10.1007/s43032-025-01958-9. 

Salas-Huetos A, Rosique-Esteban N, Becerra-Tomás N, Vizmanos B, Bulló M, Salas-Salvadó J. The effect of nutrients and dietary supplements on sperm quality parameters: a systematic review and meta-analysis of randomized clinical trials. Adv Nutr. 2018;9(6):833-848. doi:10.1093/advances/nmy057. 

Schaefer E, Nock D. The impact of preconceptional multiple-micronutrient supplementation on female fertility. Clin Med Insights Womens Health. 2019;12:1179562X19843868. doi:10.1177/1179562X19843868. 

Wallace TC, Fulgoni VL. Usual choline intakes are associated with egg and protein food consumption in the United States. Nutrients. 2017;9(8):839. doi:10.3390/nu9080839. 

Xu Y, Nisenblat V, Lu C, et al. Pretreatment with coenzyme Q10 improves ovarian response and embryo quality in low-prognosis young women with decreased ovarian reserve: a randomized controlled trial. Reprod Biol Endocrinol. 2018;16(1):29. doi:10.1186/s12958-018-0343-0. 



These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always talk with your healthcare provider before starting a new supplement, especially during pregnancy, postpartum, or while breastfeeding or taking medication.

Headshot of a smiling woman with curly blonde hair by a window, a guest featured on WeNatal's blog.

Raegen Barger, RDN, LD, IFNCP

Raegen, a registered dietitian and board-certified integrative and functional nutritionist, is passionate about supporting clients with personalized, research-based approaches to nutrition and wellness. She focuses on the generational impact of nutrition and lifestyle, helping clients improve lab markers, manage symptoms, achieve health goals, and build sustainable, balanced habits. A proud mom of two, Raegen is also a WeNatal Nutritionist.

The most important nutrients for TTC, pregnancy, postpartum recovery, and breastfeeding