Nutrition needs don’t stay static across the fertility journey and neither does your body. From the months leading up to conception through pregnancy, postpartum recovery, and breastfeeding, nutrient demands shift in meaningful ways to support hormone health, cellular energy, tissue repair, and your baby’s rapid growth and development.

While a food-first approach is always foundational, this season of life often requires more than diet alone can reliably provide. Increased nutrient needs, nausea, food aversions, sleep disruption, and stress can all make it difficult to consistently meet optimal levels of key vitamins and minerals. A comprehensive prenatal vitamin and male fertility supplement helps bridge these gaps while supporting egg and sperm quality before conception, fetal development during pregnancy, and maternal recovery and resilience postpartum and beyond.

RELATED: The ultimate preconception guide: What to do when you’re ready to get pregnant 

Essential nutrients for trying to conceive (TTC)

Preparing for pregnancy is one of the most transformative seasons in a person’s life. Physically, emotionally, and nutritionally. Long before a positive test appears, your body is already laying the foundation for conception, healthy embryo development, and a thriving pregnancy. We refer to this preconception phase as Trimester Zero®  and it’s a powerful opportunity to optimize fertility for both partners.

By intentionally supporting your nutritional status before conceiving, you build stronger reserves of key vitamins, minerals, and antioxidants that support both partners, increase your chances of conceiving, and promote a healthier pregnancy from day one.

RELATED: Can men take prenatal vitamins? 

Why preconception nutrition matters

Eggs and sperm develop over several months before conception, which means nutrition in the months leading up to pregnancy can directly influence egg quality, sperm integrity, and early embryo development. Building adequate nutrient reserves helps support healthy hormone signaling, ovulation, and implantation. When key nutrients like folate, choline, omega-3s, and antioxidants are low, oxidative stress and impaired methylation can interfere with reproductive function, highlighting why foundational nutrition before conception matters for both partners.

Key nutrients for fertility

Fertility is supported by more than one “magic” nutrient. It’s the cumulative effect of micronutrients working together to support hormone signaling, cellular energy, DNA integrity, and early embryo development. During the preconception window, certain nutrients become especially critical for egg quality, ovulation, and implantation. 

Key nutrients for fertility for her

• Folate (methylated folate): Folate supports DNA synthesis, methylation, and early fetal neural development. Using a methylated form such as L-5-MTHF may improve absorption and utilization, including in individuals with MTHFR variants.
• Choline: Choline plays a key role in cell membrane structure, methylation, neurotransmitter synthesis, and early placental development. Most women do not reach optimal intake through diet alone, making it very important in the preconception period.
• Omega-3 fatty acids (DHA): DHA helps modulate inflammation, support luteal phase function, and promote implantation. Higher omega-3 intake has been associated with improved fertility outcomes and healthier reproductive hormone patterns.
• CoQ10: Coenzyme Q10 is essential for mitochondrial ATP production and acts as a potent antioxidant. Several studies show CoQ10 supplementation may improve egg quality, embryo morphology, and ovarian response, particularly in women of advanced maternal age.
• Vitamin D (D3): Vitamin D influences reproductive hormones, ovarian reserve markers such as AMH, immune function, and implantation. Deficiency has been linked to reduced fertility and poorer assisted reproduction outcomes.
• Iron & vitamin B12: Iron and vitamin B12 support red blood cell production, oxygen transport, methylation, and overall cellular energy which are all essential for ovulation, implantation, and early pregnancy health.
• Magnesium: Magnesium plays a role in progesterone synthesis, stress resilience, glucose regulation, and sleep quality, making it foundational for cycle regulation and hormonal health.
• Zinc & selenium: Both zinc and selenium support healthy follicular development, thyroid hormone conversion, antioxidant protection, and DNA integrity. Deficiencies in either have been associated with impaired fertility and poorer reproductive outcomes.

Best ways to meet these needs

Supporting fertility is most effective when nutrition, supplementation, and personalization work together.

A food-first approach remains foundational, emphasizing high-quality proteins, healthy fats, colorful produce, and foods rich in choline, antioxidants, and omega-3s. Fatty fish, pasture-raised eggs, leafy greens, legumes, and mineral-rich whole foods help support hormone health, reduce oxidative stress, and nourish developing egg and sperm cells.

Even with a strong diet, optimal intake of key nutrients can be difficult to achieve consistently. A well-formulated prenatal for women and men’s fertility supplement can help fill micronutrient gaps and support egg and sperm development throughout their multi-month maturation cycles. Look for methylated folate, DHA/EPA, bioavailable minerals, and targeted antioxidants like CoQ10 to support mitochondrial function and reproductive health.

When possible, lab testing can further personalize preconception care. Markers such as vitamin D, ferritin, vitamin B12, thyroid function, and omega-3 status can help identify deficiencies and guide targeted nutrition and supplement strategies.

Critical nutrients during the first trimester

The first trimester is one of the most nutritionally demanding phases of pregnancy. In just a few short weeks, your baby’s organs begin forming, the neural tube closes, and the placenta starts to develop, often before you even know you’re pregnant. At the same time, nausea, vomiting, and food aversions can make eating well feel nearly impossible. 

Even with those hurdles, a few nutrients matter most during this early stage:

• Folate & choline: These nutrients support DNA methylation and early brain and organ development, laying the biochemical foundation for healthy growth. 

Found in leafy greens, lentils, asparagus, avocado, citrus, egg yolks, liver, salmon, and pastured poultry.

• Iron: Iron needs begin rising early as blood volume expands. Adequate intake supports oxygen delivery to both mother and baby. 

Sources include red meat, lentils, spinach, pumpkin seeds, and iron-fortified foods.

• Vitamin B6: Often used in evidence-based nausea protocols, vitamin B6 can support both nutrient metabolism and morning sickness relief. 

Found in bananas, potatoes, chickpeas, poultry, sunflower seeds, and salmon.

• Iodine: Iodine supports maternal thyroid function and early fetal brain development. 

Food sources include seaweed, eggs, dairy, and seafood.

• Omega-3 fatty acids (DHA): DHA is essential for early brain and retinal development. 

Fatty fish such as salmon, sardines, anchovies, trout, and herring are the best sources.

• Vitamins D3 & K2: These vitamins work together to support immune regulation and early bone development. 

Found in egg yolks, fatty fish, fermented foods, grass-fed butter, cod liver oil, and select full-fat dairy products.

RELATED: What to know about omega-3 and pregnancy

Key nutrients for the second trimester

By the second trimester, energy and appetite often improve, creating an ideal opportunity to rebuild nutrient stores as fetal growth accelerates. Blood volume continues to expand, protein needs increase, and your baby’s skeleton begins to mineralize, placing greater demand on structural and mineral nutrients.

Here are the key nutrients to prioritize during this stage:

• Protein: Protein becomes foundational in the second trimester, supplying the amino acids needed for maternal blood volume, fetal tissue growth, enzyme production, and metabolic stability. 

High-quality sources include grass-fed beef, poultry, eggs, wild-caught fish, Greek yogurt, cottage cheese, lentils, beans, organic tofu and tempeh, and collagen-rich bone broth.

• Calcium, magnesium, & vitamin D: These nutrients work together to support fetal bone development, maternal skeletal integrity, muscle function, and nervous system balance. 

Calcium-rich foods include dairy, sardines with bones, salmon with bones, tahini, chia seeds, almonds, and broccoli. 

Magnesium is supplied by pumpkin seeds, leafy greens, avocado, dark chocolate, beans, and whole grains. 

Vitamin D is best supported through sunlight exposure, fatty fish, and egg yolks.

• Choline: Choline continues to support brain and placental development, methylation, and cell membrane integrity.

Sources include egg yolks, chicken, salmon, shrimp, and legumes. 

• Iron: Iron requirements increase further as red blood cell production rises, and fetal demand grows. 

Iron-rich foods include red meat, poultry, lentils, beans, spinach, and pumpkin seeds. Pairing iron with vitamin C–rich foods such as citrus, berries, kiwi, bell peppers, tomatoes, and broccoli significantly enhance absorption.

• Omega-3 fatty acids (DHA & EPA): Omega-3s remain essential for ongoing brain, eye, and nervous system development as well as inflammation balance . 
  
  
• Fiber & electrolytes: Each of these play a growing role in supporting digestion, hydration, circulation, and healthy blood volume expansion which are common areas of concern in the second trimester. 

Fiber-rich foods include vegetables, berries, oats, beans, lentils, chia seeds, and flaxseeds. 

Electrolytes such as sodium, potassium, and chloride are supported through mineral-rich broths, coconut water, avocados, bananas, root vegetables, and lightly salting whole foods with high-quality sea or Himalayan salt.

Essential nutrients for the third trimester of pregnancy

The third trimester brings another major shift in priorities. Your baby’s brain development peaks, fat stores are laid down, and your body begins preparing for labor, delivery, and the postpartum period. Thoughtful, well-balanced nutrition during this stage can meaningfully support birth outcomes, energy for labor, and recovery after birth.

Here are the key nutrients to prioritize in the third trimester:

• Choline: Choline becomes especially critical as fetal brain development accelerates and memory centers rapidly mature. Adequate intake at this stage supports neuronal structure, placental function, and long-term cognitive development.
• Omega-3 fatty acids (DHA & EPA): DHA and EPA continue to drive advanced neural maturation, visual development, and emerging immune function.
• Iron: Iron remains a high priority to prevent anemia before delivery which is an important factor for labor endurance and postpartum recovery. 
• Hydration & electrolytes: Each becomes even more important as the body prepares for birth, supporting circulation, nerve signaling, energy levels, and healthy uterine contractions. 
• Collagen: Collagen paired with vitamin C-rich foods supports tissue integrity in the cervix, skin, and pelvic floor as tissues stretch and prepare for delivery. 

Collagen-rich foods include bone broth, slow-cooked meats, and collagen peptides, while vitamin C is found in citrus, berries, kiwi, pineapple, bell peppers, and cruciferous vegetables.

• Protein: Adequate protein remains essential to support rapid fetal growth, preserve maternal muscle mass, support enzyme production, and build nutrient reserves for postpartum recovery. At this stage, sufficient protein also supports blood sugar stability, improved satiety, and recovery capacity after birth.

RELATED: Whey protein powder for fertility and pregnancy: What the research really says

Postpartum nutrition: Essential nutrients for recovery

The postpartum period, often called the “fourth trimester”, places high nutritional demands on the body. After birth, your system is repairing tissues, restoring blood volume, recalibrating hormones, and adjusting to disrupted sleep. Nutrient needs remain elevated, and deficiencies are common if intake is inadequate.

Here are the key nutrients to prioritize for postpartum recovery:

• Iron: Iron helps replenish losses from delivery and supports oxygen transport, energy levels, and cognitive function. 
• Protein & collagen: Each are essential for tissue repair, wound healing, and rebuilding connective tissue. 
• Omega-3 fatty acids: Omega-3s reduce inflammation, support nervous system repair, and influence postpartum mood. 
• Choline supports memory, cognition, nervous system function, and liver detoxification during hormonal recalibration.
• Micronutrients like vitamin D3, K2, B-vitamins, magnesium, & iodine: Micronutrients aid immune function, energy production, sleep, nervous system regulation, and thyroid health. 

Monitoring nutrient status, particularly ferritin, B12, vitamin D, and omega-3s, helps guide replenishment. Continuing your comprehensive prenatal vitamin for 6–12 months supports recovery, alongside nutrient-dense, protein-rich meals to restore strength, regulate hormones, and promote long-term vitality.

RELATED: Thriving after birth: Tips to avoid postpartum exhaustion & depletion 

Essential nutrients for breastfeeding

Lactation places the highest nutrient demands of the reproductive cycle. Your body is continuing to recover from birth while producing nutrient-rich milk to support your baby’s growth and development. During this stage, nutrient density, adequate calories and carbohydrate intake, as well as hydration become especially important for both infant nourishment and maternal well-being.

Here are the key nutrients to prioritize while breastfeeding:

• Choline: Choline plays a direct role in breast milk composition, supporting infant brain and nervous system development, while also benefiting maternal liver and cognitive health. 
• Omega-3 fatty acids: DHA and EPA remain vital for infant visual and cognitive development and immune function. 
• Iodine: Iodine supports infant thyroid function and neurological development. 
• Calcium, magnesium, & vitamin D3: These nutrients protect maternal bone health during lactation, as calcium is transferred to breast milk.
• Vitamin B12: Vitamin B12 supports maternal energy and infant neurodevelopment, particularly important for vegetarian or vegan mothers. 

Sources include meat, poultry, fish, eggs, and dairy.

• Protein & healthy fats: Adequate protein and healthy fats fuel milk production, hormone regulation, and stable blood sugar. 
• Hydration & electrolytes: Both help to support  circulation and milk let-down. 

Certain foods may support milk supply, including oats, brewer’s yeast, fennel, and fenugreek. Hydrating and nutrient-dense snacks like collagen smoothies, yogurt, nuts, seeds, and eggs provide steady energy and help sustain consistent milk production .

RELATED: The fourth trimester: Why prenatal vitamins still matter after birth 

A note from WeNatal on nourishing the full fertility journey

At WeNatal, we believe fertility and family-building are supported over time, not in isolated moments. From Trimester Zero® through pregnancy, postpartum recovery, and breastfeeding, your nutrient needs evolve, but the goal remains the same: to support both parent and baby with thoughtful, evidence-based nutrition.

Our formulations were designed to complement the exact nutrient shifts. WeNatal for Her and WeNatal for Him provides comprehensive prenatal and fertility support with bioavailable forms of folate, iron, choline, and key micronutrients. Omega DHA+ supports brain, eye, and nervous system development throughout pregnancy and breastfeeding. Egg Quality+ offers targeted mitochondrial and antioxidant support during preconception, while Rest + Digest Magnesium supports stress resilience, sleep quality, digestion, and nervous system regulation during hormonally demanding seasons.

If you’re looking for a more complete roadmap, our Complete Fertility & Wellness Guide brings everything together with nutrition, supplementation support, lifestyle practices, and education to support your body through every phase of the fertility journey with clarity and confidence.

Because building a healthy foundation for conception, pregnancy, and beyond, isn’t about doing more. It’s about being supported, consistently, every step of the way.

RELATED: Essential nutrients for the third trimester, postpartum, and lactation 

References

Agarwal A, Parekh N, Panner Selvam MK, et al. Male Oxidative Stress Infertility (MOSI): Proposed Terminology and Clinical Practice Guidelines for Management of Idiopathic Male Infertility. World J Mens Health. 2019;37(3):296-312. doi:10.5534/wjmh.190055

Amza M, Haj Hamoud B, Sima RM, et al. Docosahexaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA)-Should They Be Mandatory Supplements in Pregnancy?. Biomedicines. 2024;12(7):1471. Published 2024 Jul 3. doi:10.3390/biomedicines12071471

Dror DK, Allen LH. Overview of Nutrients in Human Milk. Adv Nutr. 2018;9(suppl_1):278S-294S. doi:10.1093/advances/nmy022

Liu J, Mantantzis K, Kaufmann L, et al. Clinical Benefits and Safety of Multiple Micronutrient Supplementation During Preconception, Pregnancy, and Lactation: A Review. Nutr Rev. 2025;83(12):2352-2371. doi:10.1093/nutrit/nuaf079

Niu C, Lu X, Xie Y, et al. Effects of Carnitine and Coenzyme Q10 on Sperm Quality and Pregnancy Rates in Men with Unexplained Infertility: A Systematic Review and Network Meta-Analysis. Reprod Sci. 2025;32(9):2864-2876. doi:10.1007/s43032-025-01958-9

Schaefer E, Nock D. The Impact of Preconceptional Multiple-Micronutrient Supplementation on Female Fertility. Clin Med Insights Womens Health. 2019;12:1179562X19843868. Published 2019 Apr 23. doi:10.1177/1179562X19843868

Xu Y, Nisenblat V, Lu C, et al. Pretreatment with coenzyme Q10 improves ovarian response and embryo quality in low-prognosis young women with decreased ovarian reserve: a randomized controlled trial. Reprod Biol Endocrinol. 2018;16(1):29. Published 2018 Mar 27. doi:10.1186/s12958-018-0343-0