What pregnancy really demands: The nutrients that matter most for mom and baby

Preconception

Pregnancy

Supplements & Science

pregnant woman in kitchen drinking water with prenatal vitamins in hand and glass container on the kitchen counter - WeNatal prenatal vitamins

Pregnancy is one of the most metabolically demanding seasons your body will ever move through. In a matter of months, you are growing a placenta, expanding your blood volume, building an entire human being, and preparing your body for birth and recovery. All of that work runs on nutrients, and your need for many of them rises well before your belly does.

If you have ever wondered which nutrients for pregnancy truly matter, you are asking exactly the right question. The internet is full of long, overwhelming lists, and it can be hard to know where to focus. The good news is that a handful of key nutrients do most of the heavy lifting, and understanding them can help you feel more grounded and less anxious about getting everything "right."

This guide walks through the nutrients that matter most for mom and baby, what each one does, where to find it in food, and how a thoughtful prenatal can help fill the gaps that diet alone often leaves behind. You do not need a perfect diet to have a healthy pregnancy. You need a steady foundation, a little bit of knowledge, and the reassurance that small, consistent choices add up.


What are the most important nutrients for pregnancy?

The most important nutrients for pregnancy include folate, choline, iron, iodine, DHA omega-3s, protein, calcium, magnesium, zinc, and vitamins B12 and D. Together they support your baby's brain and spinal cord development, healthy blood volume, oxygen delivery, tissue growth, and your own energy and recovery. Most people benefit from a food-first approach paired with a comprehensive prenatal, since several of these nutrients are difficult to reach through diet alone.


Key takeaways

  • Pregnancy significantly increases your need for specific nutrients, and those needs often rise before you feel pregnant.
  • Folate and choline support your baby's early brain and neural tube development, making them essential from the very start.
  • Iron demand climbs as your blood volume expands, which makes iron one of the nutrients most likely to run low during pregnancy.
  • DHA omega-3s and protein support your baby's growth while helping support your own energy, muscle, and recovery.
  • A food-first approach paired with a well-formulated prenatal helps cover the gaps that diet alone often cannot fill, and for many people, adding an omega-3 DHA supplement rounds out that foundation.

Every Trimester Foundation

Every Trimester Foundation

The perfect pairing for pregnancy and postpartum health.

Why do nutrient needs increase during pregnancy?

Nutrient needs rise during pregnancy because your body is doing several enormous jobs at once. You are building new tissue, growing a placenta, increasing your blood volume, and supporting a baby whose organs, brain, and skeleton are forming rapidly. Each of these processes draws on specific vitamins, minerals, amino acids, and fatty acids.

During pregnancy, blood volume expands considerably, sometimes by close to half again its usual amount, to carry oxygen and nutrients to your growing baby through the placenta. This single change alone raises your need for iron, protein, and fluids. At the same time, your baby is drawing on your nutrient stores to build everything from neural tissue to bone.

Here is the part that surprises many people: some of the most critical developmental windows happen very early, often before a positive test or first appointment. The neural tube, which becomes the brain and spinal cord, closes within the first several weeks of pregnancy. This is why entering pregnancy with strong nutrient reserves matters so much, and why preconception nutrition is such a meaningful window of opportunity.


The most important nutrients for pregnancy, and why each one matters

While dozens of nutrients contribute to a healthy pregnancy, a core group consistently appears in research as especially important. Below is a closer look at each one, what it supports, and where you can find it in food.


Folate: The foundation of early development

Folate is one of the most well-established nutrients for pregnancy because it supports DNA synthesis, methylation, and the healthy formation of your baby's neural tube. Adequate folate status before and during early pregnancy is associated with proper neural tube development, which is why it is recommended so consistently in preconception and prenatal care.

Folate comes in more than one form. Folic acid is the form studied in the landmark neural tube research and recommended in public health guidelines. Methylfolate (L-5-MTHF) is the active form the body can use without first converting it, which can make it a helpful option for people with common MTHFR gene variants that affect how efficiently folic acid is processed. 

Food sources of folate include:

  • Dark leafy greens like spinach and romaine
  • Lentils and beans
  • Asparagus
  • Avocado
  • Citrus fruits
  • Pasture-raised egg yolks


Choline: The underrated brain-builder

Choline works closely alongside folate to support methylation, cell membrane structure, and your baby's brain development. It plays a meaningful role in the formation of neural tissue and the parts of the brain involved in memory. Research suggests that adequate maternal choline intake is associated with favorable measures of infant brain development and neurocognition.

Despite its importance, choline is easy to fall short on. The adequate intake for choline during pregnancy is set at 450 mg per day, yet an analysis of U.S. national survey data found that only about 8 to 9 percent of pregnant people reach that level through food, and many prenatal vitamins contain little to no choline. Choline, folate, and DHA work as a team for your baby's developing brain, which we explore in our guide to the nutrient trio for fetal brain development.

Food sources of choline include:

  • Egg yolks, one of the richest sources
  • Salmon and shrimp
  • Pasture-raised poultry
  • Beef and liver, with liver eaten cautiously in pregnancy because of its high preformed vitamin A content
  • Legumes


Iron: Fueling oxygen and blood volume

Iron becomes one of the highest-demand nutrients in pregnancy because your blood volume expands and your body produces more red blood cells to carry oxygen to you and your baby. Iron also helps build your baby's own iron stores for after birth. Because demand rises so quickly, iron is one of the nutrients most likely to run low during pregnancy, which is why your provider checks your levels along the way. 

Iron comes in two forms. Heme iron, from animal foods, is generally easier to absorb, while nonheme iron, from plant foods, is less readily absorbed. Pairing nonheme iron with vitamin C-rich foods can meaningfully improve absorption.

Food sources of iron include:

  • Red meat, bison, and dark-meat poultry
  • Sardines
  • Lentils, beans, and chickpeas
  • Spinach and Swiss chard
  • Pumpkin seeds

Pair these with vitamin C-rich foods like citrus, berries, bell peppers, or broccoli to support absorption.


WeNatal For Her includes a gentle form of iron, and for many people a prenatal is enough. If your provider recommends additional iron based on your labs, Iron+ pairs a chelated, gentle form of iron with vitamin C in one daily capsule.

Iron+

Iron+

18 mg of Ferrochel® iron plus Pureway® C vitamin C for enhanced absorption.

DHA omega-3 fatty acids: Building the brain and eyes

DHA is a long-chain omega-3 fatty acid that becomes structurally incorporated into your baby's brain and retina. It supports neural and visual development throughout pregnancy, with demand rising as your baby's brain growth accelerates in later trimesters. DHA also plays a role in supporting a healthy inflammatory balance for mom.

Because the body cannot efficiently produce enough DHA on its own, dietary intake matters, and many people do not eat enough low-mercury fatty fish to meet their needs.

Food sources of DHA include:

  • Salmon
  • Sardines
  • Anchovies
  • Trout and herring

If you do not regularly eat fatty fish, an omega-3 supplement can help you reach a supportive level of DHA.

Omega DHA+

WeNatal Omega DHA+ jar, a cream prenatal supplement container shown on a transparent background, offering daily omega-3 DHA nutrient support.

Optimize health with omega-3 fatty acids.

Protein: The building blocks of growth and recovery

Protein supplies the amino acids your body uses to build fetal tissue, expand your blood volume, produce enzymes and hormones, and preserve your own muscle. Protein needs climb as pregnancy progresses, and adequate intake also supports steady energy and satiety, which can be especially helpful when energy and appetite fluctuate.

One carefully designed study that measured protein needs directly in healthy pregnant women estimated requirements of about 1.2 grams per kilogram of body weight per day in early pregnancy and about 1.5 grams per kilogram in late pregnancy, both higher than current recommendations. For someone who weighs about 150 pounds (68 kg), that works out to roughly 83 to 104 grams per day. Individual needs vary, so think of this as a helpful starting point to discuss with your provider rather than a strict rule.

Food sources of protein include:

  • Grass-fed beef and pasture-raised poultry
  • Wild-caught fish and eggs
  • Greek yogurt and cottage cheese
  • Lentils, beans, and organic tofu or tempeh
  • Collagen-rich bone broth


If reaching your protein goal feels hard, especially through first-trimester nausea or a crowded stomach in the third trimester, a shake can make it easier to get there.

Prenatal Protein+ For Her

WeNatal Prenatal Protein + For Her powder pouch in vanilla flavor, shown on a transparent background.

3-in-1 prenatal, protein, and collagen for every stage.

Iodine: Supporting thyroid and brain development

Iodine supports your thyroid function, which in turn supports your baby's early brain and nervous system development. Thyroid demand increases in pregnancy, making adequate iodine intake important, especially early on.

Food sources of iodine include:

  • Seaweed
  • Eggs
  • Dairy
  • Seafood


Calcium, magnesium, and vitamin D: The structural team

These three nutrients work together to support your baby's bone development, your own skeletal integrity, muscle function, and nervous system balance. Vitamin D also plays a role in immune function, and researchers are exploring how maternal vitamin D status relates to baby's brain development, which we cover in what a 10-year study found about vitamin D in pregnancy. Magnesium supports restful sleep, a calm stress response, and healthy blood sugar levels already within the normal range.

Food sources include:

  • Calcium: dairy, sardines and salmon with bones, tahini, chia seeds, and broccoli
  • Magnesium: pumpkin seeds, leafy greens, avocado, and beans
  • Vitamin D: sunlight, fatty fish, and egg yolks


Zinc, selenium, and vitamin B12: Quiet but essential

These micronutrients support DNA integrity, cellular energy, thyroid conversion, and healthy cell division. Vitamin B12, in particular, supports red blood cell production and neurological development and is especially important for those following vegetarian or vegan diets. If that is you, our vegetarian and vegan fertility and pregnancy guide covers the nutrients worth extra attention.

Food sources include:

  • Zinc: oysters, beef, pumpkin seeds, and chickpeas
  • Selenium: Brazil nuts, tuna, eggs, and sunflower seeds
  • Vitamin B12: meat, poultry, fish, eggs, and dairy


How nutrient needs shift across each trimester

While all of these nutrients matter throughout pregnancy, their relative importance shifts as your baby grows and your body changes. Thinking about nutrition trimester by trimester can make it feel more manageable.


First trimester

This is a foundational window, even though eating well can feel hardest here because of nausea and food aversions. Folate, choline, iodine, iron, vitamin B6, and DHA are especially important as the neural tube closes and early organs form. If nausea limits your intake, focus on small, frequent, tolerable meals and lean on your prenatal to help cover gaps.


Second trimester

As energy and appetite often improve, this becomes a great time to rebuild nutrient stores. Protein needs rise, your baby's skeleton begins to mineralize, and calcium, magnesium, vitamin D, iron, choline, and DHA all take on greater importance.


Third trimester

Your baby's brain development peaks and fat stores are laid down, so choline, DHA, iron, and protein remain high priorities. Hydration, electrolytes, and collagen also become more relevant as your body prepares for labor and recovery.


Can you get all of these nutrients from food alone?

A food-first approach is always the foundation, and whole foods provide nutrients in forms and combinations that supplements cannot fully replicate. That said, meeting optimal levels of every key nutrient through diet alone is genuinely difficult during pregnancy.

Several factors make this challenging:

  • Nutrient needs rise faster than appetite sometimes allows
  • Nausea and food aversions can limit variety, especially early on
  • Some nutrients, like choline and DHA, are hard to reach even with a strong diet
  • Busy schedules, food preferences, and budget all shape what realistically ends up on your plate

This is where a comprehensive prenatal earns its place. A well-formulated prenatal is designed to help fill the gaps that food leaves behind, using bioavailable nutrient forms and thoughtful dosing rather than simply checking boxes on a label. Research on multiple-micronutrient supplementation during preconception, pregnancy, and lactation supports the general value of broad nutrient support across these stages, although much of that evidence comes from settings where deficiencies are more common, so it speaks to nutrient support in general rather than to any single product.


What should both partners know?

Preconception nutrition is not only a maternal responsibility. Sperm develop over roughly two to three months before conception, and male nutrition, lifestyle, and overall health can influence sperm quality during that window. At WeNatal, we believe men are 50% of the fertility equation, and that shared preparation can make the journey feel more connected and less isolating.

For couples in the preconception phase, this can look like both partners prioritizing nutrient-dense meals, supporting healthy habits together, and considering a prenatal suited to each person's needs, such as WeNatal For Him, which was formulated with 20 key nutrients to support healthy sperm cycles. Approaching this season as a team can lighten the emotional load and build a shared foundation before pregnancy even begins. 

Trying To Conceive Foundation

WeNatal For Him and For Her jars, teal and mauve prenatal supplement containers shown together on a transparent background, offering daily nutrient and fertility support for couples.

Complete nutrition for egg and sperm quality.


When should you talk to your provider?

Nutrition is deeply personal, and your individual needs depend on your labs, health history, diet, and pregnancy stage. It is always a good idea to loop in your provider for personalized guidance, and especially worth reaching out if you notice any of the following:

  • Persistent fatigue, dizziness, shortness of breath, or heart palpitations, which can signal low iron
  • A history of anemia, heavy periods before pregnancy, or low ferritin
  • A restrictive diet, food allergies, or a vegetarian or vegan pattern that may affect B12, iron, or DHA intake
  • Difficulty keeping food down due to severe nausea or vomiting
  • Questions about whether your prenatal is well-suited to your needs

Your provider can order labs such as ferritin, vitamin D, B12, and thyroid markers, and help you personalize both your diet and your supplement routine. Our guide to prenatal blood tests by trimester can help you know what to expect and what to ask. Supplements are meant to complement, not replace, individualized medical care.



Frequently asked questions about nutrients for pregnancy

What is the single most important nutrient during pregnancy?

There is no single most important nutrient, because pregnancy relies on many nutrients working together. That said, folate is one of the most critical in early pregnancy because it supports neural tube development, which happens in the first several weeks. Choline, iron, DHA, and protein are also consistently emphasized in research.


Do I really need a prenatal if I eat a healthy diet?

For most people, yes. Even a strong, whole-food diet can fall short of the elevated nutrient needs of pregnancy, particularly for nutrients like choline, DHA, iron, and folate. A comprehensive prenatal helps fill those gaps, working alongside your diet rather than replacing it.


When should I start taking prenatal nutrients?

Ideally, in the preconception window, since some of the most important developmental windows happen very early, often before you know you are pregnant. Starting a prenatal in the months leading up to conception helps you enter pregnancy with stronger nutrient reserves. Talk with your provider about timing that fits your situation.


Which nutrients are hardest to get from food during pregnancy?

Choline and DHA are two of the most commonly under-consumed nutrients, even among people who eat well. Iron can also be difficult to maintain as needs rise sharply, especially for those who eat little red meat or follow plant-based diets.


Can I take too many pregnancy nutrients?

Yes. More is not always better, and some nutrients, such as iron and preformed vitamin A, can cause problems in excess. This is why a thoughtfully dosed prenatal and provider guidance matter more than stacking high-dose individual supplements.


Do nutrient needs change after birth?

Yes. Postpartum recovery and breastfeeding place their own high demands on the body, and many nutrients, including iron, protein, choline, DHA, and micronutrients, remain important. Many people continue their prenatal for 6 to 12 months after birth or post-breastfeeding to support recovery, and our article on nutrient repletion after pregnancy explains why. 



A note from WeNatal on nutrients for pregnancy

At WeNatal, we believe pregnancy nutrition should feel supportive and encouraging, not like a test you are trying to pass. Your body is doing something remarkable, and it deserves to be nourished with intention and care rather than fear.

The nutrients that matter most for mom and baby, including folate, choline, iron, DHA, protein, and the wider team of vitamins and minerals, work together to support your baby's development and your own energy, resilience, and recovery. A food-first foundation will always come first, and a thoughtful prenatal can help fill the gaps that this demanding season so often creates.

WeNatal For Her was formulated with bioavailable nutrient forms, including methylated folate, choline, gentle iron, and other key micronutrients, to help support you from preconception through pregnancy and into postpartum. Because your needs shift by stage, we have grouped our formulas into simple routines:

Wherever you are right now, whether you are preparing to conceive, newly pregnant, or well along the way, you do not have to do this perfectly. You simply have to keep showing up for yourself and your baby, one nourishing choice at a time.

Shop WeNatal bundles by stage

Get the free WeNatal Pregnancy Guide






References

Amza M, Haj Hamoud B, Sima RM, et al. Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA): should they be mandatory supplements in pregnancy? Biomedicines. 2024;12(7):1471. doi:10.3390/biomedicines12071471

American College of Obstetricians and Gynecologists. Anemia in pregnancy: ACOG Practice Bulletin No. 233. 2021. 

Dror DK, Allen LH. Overview of nutrients in human milk. Adv Nutr. 2018;9(suppl 1):278S-294S. doi:10.1093/advances/nmy022

Finkelstein JL, Cuthbert A, Weeks J, et al. Daily oral iron supplementation during pregnancy. Cochrane Database Syst Rev. 2024;8(8):CD004736. doi:10.1002/14651858.CD004736.pub6

Haider BA, Olofin I, Wang M, et al. Anaemia, prenatal iron use, and risk of adverse pregnancy outcomes: systematic review and meta-analysis. BMJ. 2013;346:f3443. doi:10.1136/bmj.f3443

Liu J, Mantantzis K, Kaufmann L, et al. Clinical benefits and safety of multiple micronutrient supplementation during preconception, pregnancy, and lactation: a review. Nutr Rev. 2025;83(12):2352-2371. doi:10.1093/nutrit/nuaf079

Obeid R, Derbyshire E, Schön C. Association between maternal choline, fetal brain development, and child neurocognition: systematic review and meta-analysis of human studies. Adv Nutr. 2022;13(6):2445-2457. doi:10.1093/advances/nmac082

Soma-Pillay P, Nelson-Piercy C, Tolppanen H, Mebazaa A. Physiological changes in pregnancy. Cardiovasc J Afr. 2016;27(2):89-94. doi:10.5830/CVJA-2016-021

Stephens TV, Payne M, Ball RO, Pencharz PB, Elango R. Protein requirements of healthy pregnant women during early and late gestation are higher than current recommendations. J Nutr. 2015;145(1):73-78. doi:10.3945/jn.114.198622

Wallace TC, Fulgoni VL. Usual choline intakes are associated with egg and protein food consumption in the United States. Nutrients. 2017;9(8):839. doi:10.3390/nu9080839



These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent disease. This article is educational and is not a substitute for personalized medical advice.

Headshot of a smiling woman with curly blonde hair by a window, a guest featured on WeNatal's blog.

Raegen Barger, RDN, LD, IFNCP

Raegen, a registered dietitian and board-certified integrative and functional nutritionist, is passionate about supporting clients with personalized, research-based approaches to nutrition and wellness. She focuses on the generational impact of nutrition and lifestyle, helping clients improve lab markers, manage symptoms, achieve health goals, and build sustainable, balanced habits. A proud mom of two, Raegen is also a WeNatal Nutritionist.

pregnant woman in kitchen drinking water with prenatal vitamins in hand and glass container on the kitchen counter - WeNatal prenatal vitamins